Why 100 Markers Change Everything
Your annual physical checks 10–12 markers. Algorithm-based competitors run a single calculation. We analyze 100 markers across 12 health domains using our 7-Domain Composite Score Engine. Because your health is more than one number.
Last updated: June 9, 2026
81 Blood Markers + 19 Urinalysis Markers
At the entry tier the Executive Panel measures 81 biomarkers from your blood draw plus 19 markers from urinalysis, covering metabolic health, cardiovascular risk, inflammation, hormones, organ function, blood health, body composition, and toxin load. That's 100 total markers, more than 6x what your doctor checks. Urinalysis stays at 19 on every tier; higher care tiers add blood markers, reaching 125 on Total Optimization.
Standard Physical
10–12
markers
Algorithm Competitors
15–25
markers
Executive Panel
100
markers (81 blood + 19 urinalysis)
"Normal / abnormal"
Single bio age number
7-domain scores + composite biological age
No action plan
No clinical guidance
Protocol engine + physician consultation
A Complete Map of Your Health
Each domain scores 0–100 using optimized clinical reference ranges, not standard lab ranges that let problems hide until they're advanced.
Metabolic Health
20% weightKey markers: Fasting Glucose, Insulin, HbA1c, HOMA-IR
Cardiovascular
20% weightKey markers: ApoB, LDL-C, HDL-C, Triglycerides, Lp(a), TC/HDL Ratio
Inflammation
15% weightKey markers: hs-CRP, Homocysteine, Ferritin, ESR
Hormonal
15% weightKey markers: Total/Free Testosterone, DHEA-S, Cortisol, Estradiol, SHBG, IGF-1
Organ Function
10% weightKey markers: ALT, AST, GGT, BUN, Creatinine, eGFR, Albumin
Blood Health
10% weightKey markers: CBC with differential, Iron, TIBC, Ferritin, B12, Folate
Body Composition
10% weightKey markers: Calculated from clinical measurements. NOT BMI
7 Domains. One Composite Score. Your Biological Age.
Most biological age tests run a single algorithm and hand you one number. No context. No breakdown. No action plan. We do it differently.
100 Markers Collected
Your Executive Panel draws 81 markers from your blood plus 19 from urinalysis, covering metabolic health, cardiovascular risk, inflammation, hormones, organ function, blood health, body composition, and more.
12 Health Domains, 7 Composite Scores (0–100)
Markers are organized across 12 health domains, then distilled into 7 composite scores. Every score uses optimized clinical reference ranges, not the standard lab ranges that let problems hide until they become diagnoses. A score of 80+ means that domain is performing well. Below 70 means it needs attention.
Composite → Biological Age
The weighted composite of all 7 domain scores determines your 1836 Functional Bio Age. This isn't a black-box algorithm. You can see exactly which domains are pulling your age up or pushing it down, and your protocol targets the specific domains that need it.
Founder's Actual Results: March 2026
48.3
Functional Bio Age
52
Chronological Age
−3.7 yrs
vs. Calendar Age
8 months earlier, his Bio Age was 54.0, aging 2 years faster than his calendar. The domain scores showed metabolic health at 39/100 driving the gap. After a targeted protocol, metabolic jumped to 79/100 and biological age reversed by 5.7 years.
See the full data storyStandard Annual Physical vs. 1836 Precision Diagnostic
What your annual physical checks. And what 1836 checks instead.
| Health Domain | Standard Annual Physical | 1836 Precision Diagnostic |
|---|---|---|
| Total markers | 12–15 | 100 (up to 125 by tier) |
| Cardiovascular | Total cholesterol only | ApoB, Lp(a), ASCVD risk score, LDL particle, HDL particle, triglyceride/HDL ratio, hsCRP |
| Metabolic | Fasting glucose only | Glucose, fasting insulin, HOMA-IR, HbA1c, fructosamine, leptin, adiponectin |
| Hormonal: Men | Often skipped | Total + Free T, SHBG, Estradiol, DHEA-S, PSA, IGF-1 |
| Hormonal: Women | Often skipped | Total + Free T, SHBG, Estradiol, Progesterone, AMH, DHEA-S, FSH, LH |
| Thyroid | TSH only | TSH, Free T4, Free T3, Reverse T3, TPO antibodies |
| Inflammation | Maybe hsCRP | hsCRP, homocysteine, fibrinogen, ferritin, sed rate |
| Vitamins & Minerals | Vitamin D sometimes | Vit D, B12, folate, RBC magnesium, zinc, copper, selenium |
| Liver | ALT, AST | ALT, AST, GGT, bilirubin, alkaline phosphatase, albumin |
| Kidney | Creatinine | Creatinine, BUN, eGFR, cystatin C optional, electrolytes |
| Urinalysis | Sometimes 4-marker | 19-marker comprehensive |
| Biological age | Not measured | 1836 Functional Bio Age (7-domain composite) |
| ASCVD risk score | Sometimes calculated | Always calculated + tracked |
| Results consult | 10-minute review | 45-minute NP results consultation |
| Action plan | Prescription if abnormal | Protocol engine → tiered recommendation |